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Kidney

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Room: E-Poster Hall

P-11.168 Does the Kidney Donor Profile Index (KDPI) predict graft and patient survival in our population? Experience of a transplant center in Argentina

Maria P. Dionisi, Argentina

Teaching Instructor
Nephrology and Transplantation Division
Clinica Privada Velez Sarsfield

Abstract

Does the Kidney Donor Profile Index (KDPI) predict graft and patient survival in our population? Experience of a transplant center in Argentina

Rafael A. Maldonando1, Natalia S. Matamala1, Carlos A. Idoria1, Marisol Rodriguez1, Monica Piccardi2, Maria Dionisi1.

1Nephrology and Transplantation Division, Clinica Privada Velez Sarsfield, Cordoba, Argentina; 2Statistics and Biometrics, Faculty of Agricultural Sciences, National University of Cordoba, Cordoba, Argentina

Introduction: To verify the usefulness of the renal donor profile index (KDPI) developed by the US organ donation system as a predictor of renal graft survival in our environment and to analyze the mortality of the recipients according to the KDPI.
Methods: Retrospective, descriptive, longitudinal study of transplanted patients from our center since December 2001 to December 2014. Exclusion criteria: recipients with less than 1 year of follow-up, living donor recipients. Based on data from SINTRA (Sistema Nacional de Información de Procuración y Trasplante de la República Argentina), the KDPI was calculated. Survival analysis was performed using Kaplan-Meier curves.
Results: 218 patients were analyzed, donor age: 38.9 ± 16.1 years, recipient age: 45.72 ± 12.5 years; 70.8% of the donors were not hypertensive and 0.5% were diabetic, resulting in a KDPI of 53 ± 29%; 81.2% were standard donors and 18.8% with expanded criteria (Fig.1). Those under 50 years old had better graft survival (p = 0.014) (Fig.2). After a follow-up of 88 ± 22 months, the survival of the recipient was 98% the first year, 80% at 5 years and 73% at 16.5 years (Fig.3). It was also observed that these receptors presented different levels of survival as the KDPI increased, but was not statistically significant (p = 0.79) (Fig.4).
Conclusion: In our experience, the KDPI was limited to be considered as a tool for evaluating the quality of the kidney due to certain limitations; however, it would be appropriate to develop an index based on Argentinian or Latin-American data and the correlation with their receptor scores.

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