Long term results of living donor kidney transplantation
Aydincan Akdur1, Feza Yarbug Karakayali1, Kenan Caliskan1, Gokhan Moray1, Gulnaz Arslan2, Mehmet A. Haberal1.
1Transplantation, Baskent University, Ankara, Turkey; 2Anaesthesia, Baskent University, Ankara, Turkey
Introduction: Kidney transplantation (KT) plays an important role in the treatment of end-stage kidney disease to improve the quality of life and prolong the life of patients. This study aims to evaluate the long term results of living donor KT in our centre.
Materials and Methods: From November 1975 to December 2019, 3089 KT procedures were performed at 5 different centers (Hacettepe University, Baskent University; Ankara, Adana, Istanbul and Konya hospitals) by the same transplantation team. 2375 of them were living donor KT. We reviewed the medical records of these 2375 recipients for the following: primary cause of kidney failure, age at time of transplantation, type of graft, and medical outcomes of the recipient and donor. All living transplants were performed from related donors. There was no major donor morbidity and no donor mortality.
Results: 355 of the patients were pediatric recipient and 2020 of the patients were adult. The most common etyology for kidney transplantation was glomerulonephritis. 61,2% of the patients were female. At our institution, we perform ureteral and arterial anastomoses by means of a corner saving technique since September 2003. The rate of early urinary complications was 2,1% and the rate of late urinary complications was 0,8%. During the early postoperative period; we had 2 renal artery thrombosis (RAT) and during the late follow up period, renal arterial stenosis was identified in 3 patients. The incidence of symptomatic lymphoceles after living donor KT in our center has been 4.2%. The 5-year patient survival rates were 91.9% and the 10-year patient survival rates were 87.2 %.
Conclusions: In our center, we perform living-donor KT more than deceased-donor KT because of the paucity of organ donation. Careful evaluation of recipients and donors before transplant plays a critical step in living donor KT.
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