| 08:15 - 10:00 | Workshop Session: Beta Cell Replacement around the World - Where are we as a global community? |
| 263.1 |
Beta Cell Replacement around the World - Where are we as a global community Thomas Kay, Australia |
| 263.2 |
How can we teach/learn from one another to develop pancreas transplantation? Duck Jong Han, Korea |
| Byung-Hyun Choi, Korea |
| 263.3 |
What are the bottleneck and hurdles to overcome to expand beta cell replacement? Hussein Khambalia, United Kingdom |
| 15:15 - 17:00 | State-of-the-Art Session: Islet Transplantation Up-to-Date |
| 293.3 |
The role of extracellular matrix for successful islet transplantation Ekaterine Berishvili, Switzerland |
| 293.1 |
Overview of islet transplantation Camillo Ricordi, United States |
| 293.2 |
Islet transplantation and inflammation Maria Koulmanda, United States |
| 14:30 - 15:15 | Oral Abstracts Session: Stem Cell Transplantation and Xenotransplantation |
| 384.2 |
Quantifying the immune response to tissue engineered extracellular matrix Ryaan EL-Andari, Canada |
| 384.1 |
Simple Limbal Epithelial Transplantation (SLET) in a patient with limbal stem cell deficiency Dilek Dursun Altinors, Turkey |
| 384.3 |
Successful long-term TMA- and rejection-free survival of a kidney xenograft with triple xenoantigen knockout plus insertion of multiple human transgenes David Ma, United States |
| 15:15 - 17:00 | Workshop Session: Novel Strategies in Support to Hepatocyte Transplant |
| 394.4 |
Human liver stem cell-derived extracellular vesicles Giovanni Camussi, Italy |
| 394.2 |
Hepatic spheroids Volker Lauschke, Sweden |
| 394.1 |
Hepatocyte transplantation overview Anil Dhawan, United Kingdom |
| 23:30 - 00:15 | Oral Abstracts Session: Cell and Novel Therapies |
| 412.1 |
Human mesenchymal-stem-cells derived exosomes play important roles in enhancing CB-treg suvival and functional stability Juan Zhang, People's Republic of China |
| 412.3 |
Targeting CD4+ T cell metabolism provides an effective and age-specific immunosuppression Yeqi Nian, People's Republic of China |
| 412.4 |
Long-term follow-up of a phase 2 clinical trial to induce tolerance in living donor renal transplant recipients Joseph R. Leventhal, United States |
| 15:15 - 17:00 | State-of-the-Art Session: Beta Cell Replacement for the Future: Views from the Three Musketeers |
| 492.1 |
The view from endocrinology Eelco J..P de Koning, Netherlands |
| 492.2 |
The view from surgery Silke V. Niederhaus, United States |
| 492.3 |
The view from regenerative medicine Giuseppe Orlando, United States |
| Poster Session: Basic and Translational Sciences |
| P-2.02 |
B-cell depletion with anti-CD20 mAb exacerbates anti-donor CD4 positive T-Cell responses in highly sensitized transplant model Asuka Tanaka, Japan |
| P-2.03 |
Noninvasive genotyping of donor’s HLA in kidney transplant patients by target capture sequencing Liu Feng, People's Republic of China |
| P-2.04 |
Clinical significance of pretransplant donor-specific HLA antibodies in kidney transplant recipients of hispanic population Idalia Parra-Avila, Mexico |
| P-2.05 |
Female complexity: High ‘natural’ ABO anti-A antibodies and IgG class switch in female vs male mice Bushra Anjum, Canada |
| P-2.10 |
Immune reconstitution after autologous hematopoietic stem cell transplantation in multiple myeloma patients as a basis for early vaccination with T-cell dependent vaccines Igor Stoma, Belarus |
| P-2.11 |
Imbalance favouring follicular helper T cells over IL10+ regulatory B cells is detrimental for the renal allograft Alberto Utrero-Rico, Spain |
| P-2.13 |
Extracellular vesicles from urine as biomarkers of kidney allograft injury: optimization of extracellular vesicle isolation and characterization Ivana Sedej, Slovenia |
| P-2.14 |
Establishment of early warning model of acute rejection in combination with HLA-G 14-bp gene polymorphism, serum KIM-1and OPN Zhankui Jin, People's Republic of China |
| P-2.15 |
Immunosuppression affects circulating follicular regulatory T cells in kidney transplant recipients Carla C. Baan, Netherlands |
| P-2.16 |
The use of dd-cfDNA as a predictive tool for future proteinuria Thierry Viard, United States |
| P-2.17 |
Characterization of an integrative prognostic score for US patients taken from the DART study Thierry Viard, United States |
| P-2.18 |
dd-cfDNA as a risk factor for initiating de-novo donor specific antibodies in heart transplantation Thierry Viard, United States |
| P-2.19 |
Factors influencing background cell-free DNA levels: Implications for donor derived cell-free DNA assessment in transplant patients Trudy McKanna, United States |
| P-2.20 |
Anti-rejection therapy does not eliminate donor-reactive IFN-γ and IL-21 producing cells Nicole M. van Besouw, Netherlands |
| P-2.22 |
Use of dd-cfDNA as a surrogate marker of injury following hypothermic machine perfusion Thierry Viard, United States |
| P-2.23 |
Establishment of early diagnostic model of acute rejection in combination with IL-2, IL-6, TNF-α and IFN-γ Zhankui Jin, People's Republic of China |
| P-2.24 |
Incidence and risk factors of new onset diabetes after solid organ transplantation: Baskent University experience Didem Turgut, Turkey |
| P-2.25 |
Value of dd-cfDNA when considering recipient ethnicity to further to help risk stratify transplant recipients Thierry Viard, United States |
| P-2.26 |
Long-lasting effects of anti-rejection therapy on natural antibodies and alloreactive T cells in kidney transplant patients Nicole M. van Besouw, Netherlands |
| P-2.27 |
Podocyte-specific urinary extracellular vesicles: A novel biomarker for recurrent primary focal segmental glomerulosclerosis after kidney transplantation Hien Lau, United States |
| P-2.29 |
The relationship between myocardial fibrosis and plasma level of galectin-3 in heart transplant recipients underwent acute rejection Rivada Kurabekova, Russian Federation |
| P-2.30 |
Do the blood groups and HLA types have a role in end stage chronic renal failure pathogenesis? A comparative retrospective single-center study Ugur Musabak, Turkey |
| P-2.31 |
Immune signs of accommodation in kidney transplant recipients Maciej Zieliński, Poland |
| P-2.33 |
The utility of QuantiFERON monitoring based assay in assessing clinical events among kidney transplant recipients Maisarah Jalalonmuhali, Malaysia |
| P-2.37 |
IL-21 as a new target for immunosuppressive therapies Carla C. Baan, Netherlands |
| P-2.38 |
The small-molecule BCL6-inhibitor 79-6 suppresses follicular T helper cell differentiation and plasma blast formation Rens Kraaijeveld, Netherlands |
| P-2.39 |
Intra-lymph node delivery of macroparticles loaded with rapamycin in non-human primates Zahra Habibabady, United States |
| P-2.40 |
Clinical-experimental experience with rapamycin in visceral transplantation Javier Serradilla, Spain |
| P-2.41 |
The effects of a novel drug, PQA 18, on small intestinal transplantation Tasuku Kodama, Japan |
| P-2.45 |
Cyclic helix B peptide ameliorates renal fibrosis induced by unilateral ureter obstruction via inhibiting NLRP3 pathway Cheng Yang, People's Republic of China |
| P-2.47 |
The preventive effect of sirolimus on ureteral stricture formation Sanem Cimen, Turkey |
| P-2.49 |
Primate tolerance model demonstrates longer kidney graft survival with the administration of polyclonal ex-vivo expanded Tregs Karina Bruestle, United States |
| P-2.50 |
IL-4 regulates the secretion of IL-10 by human B cells Griffith Perkins, Australia |
| P-2.51 |
Immunomodulation with SA-PDL1 protein on pancreatic islets promotes indefinite graft survival in allogeneic recipients Esma ESY Yolcu, United States |
| P-2.53 |
Anti-IL-6 antibody reduces endothelial mediated pro-inflammatory responses and after binding of HLA-specific DSA to endothelial cells Nuala Mooney, France |
| P-2.54 |
Preclinical study for tolerance induction to liver allografts with rapid immunosuppression withdrawal in Cynomolgus monkeys Hiroshi Sakai, United States |
| P-2.55 |
Strong engagement of Cd137 suppresses graft-versus-host disease through dendritic cells Sang Jun Park, Korea |
| P-2.59 |
The requirement of thymic irradiation for induction of mixed chimerism and renal allograft tolerance in non-human primates Takayuki Hirose, United States |
| P-2.60 |
Experimental evidence on the role of the spleen in graft versus host disease after visceral transplantation Pablo Stringa, Argentina |
| P-2.62 |
Advantages of rhesus macaques in a tolerance model for combined bone marrow and kidney transplantation Karina Bruestle, United States |
| P-2.63 |
siRNA gene knockdown with functionalised porous silicon nanoparticles Sebastian O Stead, Australia |
| P-2.66 |
Class II HLA eplet mismatch is related to anti-donor CD4+ T cell response and de novo donor-specific antibody development in kidney transplantation recipient Hiroaki Yamane, Japan |
| P-2.70 |
Changes in phenotype of human CD4+CD25+CD127lo Treg subpopulations after culture with rIL-2 and alloantigen Nirupama D Verma, Australia |
| P-2.73 |
Mobilization of mast cells and regulatory t-cells by tetrahydrobiopterin is associated with prolonged allograft survival Manuel Maglione, Austria |
| P-2.82 |
INT 767 – A novel dual farnesoid-X receptor (FXR) and takeda G-protein-coupled receptor-5 (TGR5) agonist attenuates intestinal ischemia reperfusion injury Emilio Canovai, Belgium |
| P-2.84 |
High-mobility group box 1 protein antagonizes the immunosuppressive capacity and therapeutic effect of mesenchymal stem cells in acute kidney injury Cheng Yang, People's Republic of China |
| P-2.85 |
Mesenchymal stem cell-derived exosomes suppress of NLRP3 inflammasome activation to enhance anti-anoxic ability of porcine islets Wei Nie, People's Republic of China |
| P-2.95 |
A novel rodent model of severe renal ischemia reperfusion injury that better mimics the renal transplant recipient Ryan Ghita, United Kingdom |
| P-2.96 |
Ischemic preconditioning ameliorates renal ischemia-reperfusion injury through activating the Nrf2/HO-1 pathway enhanced autophagy in mice Jeongkye Hwang, Korea |
| P-2.99 |
In-depth assessment of ischemia/reperfusion injury in a murine model of hindlimb transplantation Franka Messner, Austria |
| P-2.103 |
Ischemic preconditioning attenuates renal ischemia-reperfusion injury by TLR4 suppression and eNOS activation Jeongkye Hwang, Korea |
| P-2.104 |
The impact of oxygen free radical scavenger on acute rejection in a histocompatible miniature swine model Philipp Tratnig-Frankl, United States |
| P-2.105 |
The tissue Common Response Module (tCRM) score provides a quantitative objective biopsy score to assess the severity of pancreas transplant rejection Yvonne Kelly, United States |
| P-2.107 |
Increased level of serum cholesterol and apoptosis together induces the development of liver fibrosis and early allograft loss Binnaz Handan Ozdemir, Turkey |
| P-2.108 |
Analyzing interactions between donor endothelium and recipient blood under flow conditions in vitro Margaret Connolly, United States |
| P-2.113 |
Influence of β-Catenin on the proliferation of vascular smooth muscle cells and the development of cardiac allograft vasculopathy in mice Christian Heim, Germany |
| P-2.115 |
Recipient bone marrow Treg; major players in transplant tolerance Amy Prosser, Australia |
| P-2.116 |
High-fibre diet reduces transplant-associated dysbiosis and improves renal allograft survival in a murine model of kidney allograft rejection Julian Singer, Australia |
| P-2.119 |
Gut microbiome dynamics over a course of kidney transplantation: Preliminary results of a pilot study Igor Stoma, Belarus |
| P-2.121 |
Characterization of donor and recipient myeloid cells following congenic and allogeneic liver transplantation Sarah J Dart, Australia |
| P-2.122 |
Preparation of transplantable acellular scleral graft using porcine eye Kyungmee Park, Korea |
| P-2.123 |
Preparation of ultra-thin descemet's membrane graft using decellularized porcine cornea Kyungmee Park, Korea |
| P-2.124 |
NK cell exhaustion facilitates tumor recurrence after liver transplantation via the TLR4 / HLA-E signaling pathway Xinxiang Yang, People's Republic of China |
| P-2.126 |
Assessment of HLA typing performance of Korea Biobank Array for transplantation genome-wide association study in Koreans Young Jin Kim, Korea |
| P-2.129 |
A genome-wide association study identified genetic loci for end-stage renal disease in the Korean population Young Jin Kim, Korea |
| P-2.130 |
Vascular endothelial growth factor (vegf) 936 C/T gene polymorphism in renal transplant recipients: Association with graft rejection and final graft outcome Manzoor Parry, India |
| P-2.131 |
Lymphotoxin beta receptor regulates Treg stability, migration, and function Vikas Saxena, United States |
| P-2.133 |
Liver tissue-resident lymphocytes are significantly heterogeneous, and the original repertoire is not recreated by infiltrating recipient cells Amy Prosser, Australia |
| P-2.137 |
Ischemic and perfused kidney treated with non-cultured adipose-derived regenerative cells increase the immune and regulatory transcriptome Ryan Ghita, United Kingdom |
| Poster Session: Cellular and Regenerative Therapies |
| P-3.06 |
Generation of stable human induced regulatory T-cells requires optimal rapamycin concentration and TCR stimulation Juewan Kim, Australia |
| P-3.11 |
Small-for-size syndrome is characterized with PD-L1 upregulation in macrophage and blocking PD-L1 accelerates liver regeneration Ji-Hua Shi, People's Republic of China |
| P-3.14 |
Directed differentiation of iPS into imDCs under the action of SN can induce immunoreactivity in vitro Cuixiang Xu, People's Republic of China |
| P-3.15 |
Sinomenine enhances imDC derived from IPS cell-directed differentiation to induce transplant immune hyporesponsiveness in mouse Cuixiang Xu, People's Republic of China |
| P-3.03 |
Cell therapy using CD8+Tregs in human transplantation Séverine Bézie, France |
| P-3.10 |
Bile duct reconstruction using scaffold-free tubular constructs created by a Bio-3D Printer for transplantation Takashi Hamada, Japan |
| P-3.13 |
Visual rehabilitation after penetrating keratoplasty Leyla Asena, Turkey |
| P-3.16 |
Limbal stem cell transplantation for restoration of the ocular surface health in bilateral limbal stem cell deficiency Dilek Dursun Altinors, Turkey |
| P-3.01 |
Mass Cytometry Analysis of the Peripheral Regulatory T cell Compartment after Cellular Therapy in Renal Transplantation Alaa Alzhrani, United Kingdom |
| P-3.08 |
Successful induction of hematopoietic chimerism by MCL-1 and Bcl-2 inhibition without radiation/chemo therapy in nonhuman primates David Ma, United States |
| Poster Session: Pancreas and Islet |
| P-14.02 |
The expression of cadherins in the development of neonatal pig islets post-transplantation Wenlong Huang, Canada |
| P-14.11 |
Bone marrow mesenchymal stem cells inhibit the effect of TIMP3 by transmitting miR-21-5p, thus improving the angiogenesis of rat islets Jingwen Wang, People's Republic of China |
| P-14.12 |
Upregulation of islet-1 in islets co-cultured with bone marrow mesenchymal stem cells promotes angiogenesis through NF-κB pathways Ying Wang, People's Republic of China |
| P-14.09 |
The advanced mechanisms of islet-engraftment onto white adipose tissue Naoaki Sakata, Japan |
| P-14.15 |
Efficacy and safety of islet transplantation in patients with type 1 diabetes: A Japanese single-center experience Takayuki Anazawa, Japan |
| P-14.16 |
Inhibition of NLRP3 inflammasome reduces apoptosis of islets and migration of macrophages after islet transplantation Taisuke Matsuoka, Japan |
| P-14.10 |
Islet isograft transplantation improves insulin sensitivity in type 2 diabetes mice induced by high fat diet combined with low-dose streptozotocin Sung Shin, Korea |
| P-14.19 |
How we achieved 0% of thrombotic graft loss -The initial 60 cases of pancreas transplant Byung-Hyun Choi, Korea |
| P-14.24 |
Beneficial effects of post-transplant dipeptidyl peptidase administration early after pancreas transplantation to improve β cell function Sung Shin, Korea |
| P-14.17 |
Lower extremity vascular complications after simultaneous pancreas kidney transplant Hillary J Braun, United States |
